A one-bead, one-stock solution approach to chemical genetics: part 2.

@article{Clemons2001AOO,
  title={A one-bead, one-stock solution approach to chemical genetics: part 2.},
  author={P. Clemons and A. Koehler and B. Wagner and T. G. Sprigings and D. R. Spring and R. W. King and S. L. Schreiber and M. Foley},
  journal={Chemistry & biology},
  year={2001},
  volume={8 12},
  pages={
          1183-95
        }
}
BACKGROUND Chemical genetics provides a systematic means to study biology using small molecules to effect spatial and temporal control over protein function. As complementary approaches, phenotypic and proteomic screens of structurally diverse and complex small molecules may yield not only interesting individual probes of biological function, but also global information about small molecule collections and the interactions of their members with biological systems. RESULTS We report a general… Expand
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