A one‐year study to assess the safety and efficacy of the CB1R inverse agonist taranabant in overweight and obese patients with type 2 diabetes

@article{Kipnes2010AOS,
  title={A one‐year study to assess the safety and efficacy of the CB1R inverse agonist taranabant in overweight and obese patients with type 2 diabetes},
  author={Mark S. Kipnes and Priscilla A. Hollander and Ken Fujioka and Ira Gantz and Thomas L Seck and Ngozi Erondu and Yue Shentu and Kaifeng Lu and Shailaja Suryawanshi and M Chou and Amy O. Johnson‐Levonas and S. B. Heymsfield and Deborah R. Shapiro and Keith D. Kaufman and John M. Amatruda},
  journal={Diabetes},
  year={2010},
  volume={12}
}
Aim: To evaluate the efficacy and safety of taranabant in overweight and obese patients with type 2 diabetes mellitus (T2DM). 
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A clinical trial assessing the safety and efficacy of taranabant, a CB1R inverse agonist, in obese and overweight patients: a high-dose study
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Taranabant at the 2- and 4-mg dose was effective in achieving clinically significant weight loss over 2 years and was associated with dose-related increases in adverse experiences.
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