A novel vitamin C analog, 2-O-(beta-D-Glucopyranosyl)ascorbic acid: examination of enzymatic synthesis and biological activity.

@article{ToyadaOno2005ANV,
  title={A novel vitamin C analog, 2-O-(beta-D-Glucopyranosyl)ascorbic acid: examination of enzymatic synthesis and biological activity.},
  author={Yoshiko Toyada-Ono and Mitsuru Maeda and Masahiro Nakao and Makiko Yoshimura and Namino Sugiura-Tomimori and Harukazu Fukami and Hitomi Nishioka and Yayoi Miyashita and Shosuke Kojo},
  journal={Journal of bioscience and bioengineering},
  year={2005},
  volume={99 4},
  pages={361-5}
}
2-O-(beta-D-Glucopyranosyl)ascorbic acid (AA 2 beta G) isolated from a popular traditional Chinese food (Lycium fruit) was synthesized using cellulase derived from Trichoderma sp. with cellobiose as a glucose donor. 6-O-(beta-D-Glucopyranosyl)ascorbic acid as well as AA 2 beta G was also synthesized in this reaction. The vitamin C activity of AA 2 beta G was also evaluated using inherently scorbutic (osteogenic disorder Shionogi [ODS]) rats. The rats were fed vitamin C-deficient food and water… CONTINUE READING