A novel vasorelaxant lectin purified from seeds of Clathrotropis nitida: partial characterization and immobilization in chitosan beads.

@article{Alves2015ANV,
  title={A novel vasorelaxant lectin purified from seeds of Clathrotropis nitida: partial characterization and immobilization in chitosan beads.},
  author={Ana Cec{\'i}lia Alves and Mayron Alves de Vasconcelos and Mayara Queiroz Santiago and Vanir Reis Pinto-Junior and Vinicius Jos{\'e} Silva Osterne and Claudia Figueiredo Lossio and Pedro Henrique de Souza Ferreira Bringel and Rondinelle Ribeiro Castro and Celso S Nagano and Pl{\'i}nio Delatorre and Luiz Augusto Gomes Souza and Kyria S Nascimento and Ana Maria S Assreuy and Benildo Sousa Cavada},
  journal={Archives of biochemistry and biophysics},
  year={2015},
  volume={588},
  pages={
          33-40
        }
}
A novel lectin from seeds of Clathrotropis nitida (CNA) was purified and characterized. CNA is a glycoprotein containing approximately 3.3% carbohydrates in its structure. CNA promoted intense agglutination of rabbit erythrocytes, which was inhibited by galactosides and porcine stomach mucin (PSM). The lectin maintained its hemagglutinating activity after incubation in a wide range of temperatures (30-60 °C) and pH (6.0-7.0), and its binding activity was dependent on divalent cations (Ca(+2… CONTINUE READING
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