A novel variant of the MHC-linked hsp70, hsp70-hom, is associated with rheumatoid arthritis.

@article{Jenkins2000ANV,
  title={A novel variant of the MHC-linked hsp70, hsp70-hom, is associated with rheumatoid arthritis.},
  author={Suzanne C. Jenkins and Ruth E March and Robert D. Campbell and Caroline M. Milner},
  journal={Tissue antigens},
  year={2000},
  volume={56 1},
  pages={38-44}
}
The three major histocompatibility complex (MHC)-linked hsp70s have been screened for variation in their 28 kDa C-terminal regions by direct nucleotide sequencing of the corresponding DNA fragments. No amino acid variation was detected in the major heat-inducible hsp70 (encoded by hsp70-1 and hsp70-2), although previously unreported silent mutations were identified in all three of the MHC-linked hsp70 genes. A novel coding polymorphism, a G to A transition, was identified at nucleotide 2763 of… CONTINUE READING
10 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

Similar Papers

Loading similar papers…