A novel ubiquitously distributed isoform of GIRK2 (GIRK2B) enhances GIRK1 expression of the G-protein-gated K+ current in Xenopus oocytes.

@article{Isomoto1996ANU,
  title={A novel ubiquitously distributed isoform of GIRK2 (GIRK2B) enhances GIRK1 expression of the G-protein-gated K+ current in Xenopus oocytes.},
  author={Shojiro Isomoto and Chiharu Kondo and Nami Takahashi and Seiji Matsumoto and Mitsuhiko Yamada and Toru Takumi and Yoshiyuki Horio and Yoshihisa Kurachi},
  journal={Biochemical and biophysical research communications},
  year={1996},
  volume={218 1},
  pages={286-91}
}
We have isolated a novel variant form of GIRK2, designated GIRK2B, from mouse brain cDNA library. GIRK2B was much shorter than the first type of GIRK2 (GIRK2A), but its amino acid sequence was identical to the corresponding part of GIRK2A except the C-terminal eight amino acid residues. When GIRK2B cRNA was co-injected with GIRK1 and m2-receptor cRNAs to… CONTINUE READING