A novel tumour associated leucine zipper protein targeting to sites of gene transcription and splicing

@article{Treci2002ANT,
  title={A novel tumour associated leucine zipper protein targeting to sites of gene transcription and splicing},
  author={{\"O}zlem T{\"u}reci and Uğur Şahin and Michael Koslowski and Benedikt Buss and Carolin Bell and Pia Ballweber and Carsten Zwick and Thomas Eberle and M X Zuber and Carlos Villena-Heinsen and Gerhard Seitz and Michael Pfreundschuh},
  journal={Oncogene},
  year={2002},
  volume={21},
  pages={3879-3888}
}
We describe here the definition and characterization of antigen CT-8/HOM-TES-85 encoded by a previously unknown gene and identified by serological expression screening using antibodies from a seminoma patient. Intriguingly, the leucine zipper region of CT-8/HOM-TES-85 shows an atypical amphipathy with clusters of hydrophobic residues that is exclusively shared by the N-myc proto-oncogene. CT-8/HOM-TES-85 gene is tightly silenced in normal tissues except for testis. However, it is frequently… 
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