A novel transglutaminase substrate from Streptomyces mobaraensis inhibiting papain-like cysteine proteases.

@article{Sarafeddinov2011ANT,
  title={A novel transglutaminase substrate from Streptomyces mobaraensis inhibiting papain-like cysteine proteases.},
  author={Alla Sarafeddinov and Atia Arif and Anna Peters and Hans-Lothar Fuchsbauer},
  journal={Journal of microbiology and biotechnology},
  year={2011},
  volume={21 6},
  pages={
          617-26
        }
}
Transglutaminase from Streptomyces mobaraensis is an enzyme of unknown function that cross-links proteins to high molecular weight aggregates. Previously, we characterized two intrinsic transglutaminase substrates with inactivating activities against subtilisin and dispase. This report now describes a novel substrate that inhibits papain, bromelain, and trypsin. Papain was the most sensitive protease; thus, the protein was designated Streptomyces papain inhibitor (SPI). To avoid… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 42 REFERENCES

Poly-gamma-glutamate in bacteria.

  • Molecular microbiology
  • 2006
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

Similar Papers

Loading similar papers…