A novel transgenic zebrafish model for blood-brain and blood-retinal barrier development

@inproceedings{Xie2010ANT,
  title={A novel transgenic zebrafish model for blood-brain and blood-retinal barrier development},
  author={Jing Xie and Eric Farage and Masahiko Sugimoto and Bela Anand-Apte},
  booktitle={BMC Developmental Biology},
  year={2010}
}
Development and maintenance of the blood-brain and blood-retinal barrier is critical for the homeostasis of brain and retinal tissue. Despite decades of research our knowledge of the formation and maintenance of the blood-brain (BBB) and blood-retinal (BRB) barrier is very limited. We have established an in vivo model to study the development and maintenance of these barriers by generating a transgenic zebrafish line that expresses a vitamin D-binding protein fused with enhanced green… CONTINUE READING
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