A novel time-varying poly lactic-co glycolic acid external sheath for vein grafts designed under physiological loading.

@article{Liao2007ANT,
  title={A novel time-varying poly lactic-co glycolic acid external sheath for vein grafts designed under physiological loading.},
  author={Sophia W Liao and Xiao Yun Lu and Andrew J Putnam and Ghassan S. Kassab},
  journal={Tissue engineering},
  year={2007},
  volume={13 12},
  pages={2855-62}
}
Changes in dimensional and mechanical properties of degradable sheaths in poly lactic-co glycolic acid (PLGA) have been researched extensively. Composite PLGA having variable resorption rates in multiple layers under physiological loading has not been reported. Our novel design of a PLGA sheath is composed of 3 layers with different degradation rates (i.e., the innermost layer degrades the fastest, followed by the middle, while the outer layer degrades the slowest). In the presence of… CONTINUE READING