A novel thiol-modified hyaluronan and elastin-like polypetide composite material for tissue engineering of the nucleus pulposus of the intervertebral disc.

@article{Moss2011ANT,
  title={A novel thiol-modified hyaluronan and elastin-like polypetide composite material for tissue engineering of the nucleus pulposus of the intervertebral disc.},
  author={Isaac L. Moss and Lyle M Gordon and Kimberly A. Woodhouse and Cari Whyne and Albert Juang Ming Yee},
  journal={Spine},
  year={2011},
  volume={36 13},
  pages={1022-9}
}
STUDY DESIGN Biomechanical, in vitro, and initial in vivo evaluation of a thiol-modified hyaluronan (TM-HA) and elastin-like polypeptide (ELP) composite hydrogel for nucleus pulposus (NP) tissue engineering. OBJECTIVE To investigate the utility of a TM-HA and ELP composite material as a potential tissue-engineering scaffold to reconstitute the NP in early degenerative disc disease (DDD) on the basis of both biomechanical and biologic parameters. SUMMARY OF BACKGROUND DATA DDD is a common… CONTINUE READING
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