A novel synthetic adjuvant enhances dendritic cell function.

  title={A novel synthetic adjuvant enhances dendritic cell function.},
  author={Karen S. M. Phillipps and Michelle N. Wykes and Xue Qin Liu and Melissa Brown and Joanne T. Blanchfield and Istvan Toth},
  volume={128 1 Suppl},
The lipid core peptide (LCP) is a novel, synthetic, self-adjuvanted vaccine delivery system that neatly incorporates the adjuvant, carrier and antigenic peptides of a vaccine into a single molecular entity. This system has been previously shown to efficiently deliver vaccines and induce immunity. Because adjuvants target sentinels of the immune response, such as dendritic cells (DCs), that are widely distributed throughout the body to initiate specific immune responses, we investigated the… CONTINUE READING
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