A novel synthetic adjuvant enhances dendritic cell function.

@article{Phillipps2009ANS,
  title={A novel synthetic adjuvant enhances dendritic cell function.},
  author={Karen S. M. Phillipps and Michelle N. Wykes and Xue Qin Liu and Melissa Brown and Joanne T. Blanchfield and Istvan Toth},
  journal={Immunology},
  year={2009},
  volume={128 1 Suppl},
  pages={e582-8}
}
The lipid core peptide (LCP) is a novel, synthetic, self-adjuvanted vaccine delivery system that neatly incorporates the adjuvant, carrier and antigenic peptides of a vaccine into a single molecular entity. This system has been previously shown to efficiently deliver vaccines and induce immunity. Because adjuvants target sentinels of the immune response, such as dendritic cells (DCs), that are widely distributed throughout the body to initiate specific immune responses, we investigated the… CONTINUE READING
11 Citations
39 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 39 references

Toll-like receptor 2 agonist Pam3CSK4 enhances the induction of antigen-specific tolerance via the sublingual route

  • V Lombardi, vL Overtvelt, S Horiot
  • Clin Exp Allergy
  • 2008

Similar Papers

Loading similar papers…