A novel synthesis of protected glucose intermediates

  title={A novel synthesis of protected glucose intermediates},
  author={D. Becker and N. Galili},
  journal={Tetrahedron Letters},
  • D. Becker, N. Galili
  • Published 1992
  • Chemistry
  • Tetrahedron Letters
  • The 1,2,4,6-Tetra-O-pivaloyl-D-gluco-pyranose 3 and 1,2,3,6-Tetra-O-pivaloyl-D-gluco-pyranose 4 have been prepared in one step from anhydrous glucose and pivaloyl chloride. These new intermediates can be converted into the corresponding esters, or used in the synthesis of a disaccharide in good yield. Thus, 2,3,6-Tri-O-pivaloyl-gluco-pyranose 10 can be prepared from 4, and used for preparation of β-gluco derivatives via the corresponding trichloroacetimidate 12. 
    9 Citations
    Synthesis and utilization of saccharide intermediates.
    • 5
    Bioassay based screening of steroid derivatives in animal feed and supplements.
    • 10
    The glycosylation of steroids
    • 55
    Steroids: reactions and partial syntheses.
    • V. Černý
    • Biology, Medicine
    • Natural product reports
    • 1994
    • 2