A novel surface-based geometric approach for 3D dendritic spine detection from multi-photon excitation microscopy images

@article{Li2009ANS,
  title={A novel surface-based geometric approach for 3D dendritic spine detection from multi-photon excitation microscopy images},
  author={Qing Li and Xiaobo Zhou and Zhigang Deng and Matthew Baron and Merille A. Teylan and Yong Kim and Stephen T. C. Wong},
  journal={2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro},
  year={2009},
  pages={1255-1258}
}
Determining the relationship between the dendritic spine morphology and its functional properties is a fundamental while challenging problem in neurobiology research. In particular, how to accurately and automatically analyze meaningful structural information from a large microscopy image dataset is far away from being resolved. In this paper, we propose a novel method for the automated neuron reconstruction and spine detection from fluorescence microscopy images. After image processing… CONTINUE READING

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