A novel subtype classification and risk of breast cancer by histone modification profiling

@article{Chen2016ANS,
  title={A novel subtype classification and risk of breast cancer by histone modification profiling},
  author={Xiaohua Chen and Hanyang Hu and Lin He and Xueyuan Yu and Xiangyu Liu and Rong Zhong and Maoguo Shu},
  journal={Breast Cancer Research and Treatment},
  year={2016},
  volume={157},
  pages={267-279}
}
Breast cancer has been classified into several intrinsic molecular subtypes on the basis of genetic and epigenetic factors. However, knowledge about histone modifications that contribute to the classification and development of biologically distinct breast cancer subtypes remains limited. Here we compared the genome-wide binding patterns of H3K4me3 and… CONTINUE READING