A novel strategy of cancer gene therapy by transcriptional targeting of an allogeneic histocompatibility transgene.

@article{Kuwada2009ANS,
  title={A novel strategy of cancer gene therapy by transcriptional targeting of an allogeneic histocompatibility transgene.},
  author={Eri Kuwada and Katsuo Noguchi and Naohiro Seo and Hiromichi Yamashiro and Kohji Egawa},
  journal={Anticancer research},
  year={2009},
  volume={29 4},
  pages={1015-22}
}
BACKGROUND A drawback of cancer gene therapy is the failure of toxic gene introduction into a proportion of the tumor cells, resulting in re-progression of the disease. Cancer cell-specificity of the gene introduction has also been problematic. MATERIALS AND METHODS Previously defined promoter/enhancer DNA of Q5 tumor antigen gene was used for the purpose… CONTINUE READING