A novel strategy for microarray quality control using Bayesian networks

@article{Hautaniemi2003ANS,
  title={A novel strategy for microarray quality control using Bayesian networks},
  author={Sampsa Hautaniemi and Henrik Edgren and Petri Vesanen and Maija Wolf and Anna-Kaarina J{\"a}rvinen and Olli P. Yli-Harja and Jaakko Astola and Olli-P. Kallioniemi and Outi Monni},
  journal={Bioinformatics},
  year={2003},
  volume={19 16},
  pages={2031-8}
}
MOTIVATION High-throughput microarray technologies enable measurements of the expression levels of thousands of genes in parallel. However, microarray printing, hybridization and washing may create substantial variability in the quality of the data. As erroneous measurements may have a drastic impact on the results by disturbing the normalization schemes and by introducing expression patterns that lead to incorrect conclusions, it is crucial to discard low quality observations in the early… CONTINUE READING