A novel single nucleotide polymorphism in XRCC4 gene is associated with oral cancer susceptibility in Taiwanese patients.

@article{Chiu2008ANS,
  title={A novel single nucleotide polymorphism in XRCC4 gene is associated with oral cancer susceptibility in Taiwanese patients.},
  author={C F Chiu and Ming-Hsui Tsai and Hsien-Chang Tseng and Cheng-li Wang and Chung-Hsing Wang and Cheng-Nan Wu and C T Lin and Da-Tian Bau},
  journal={Oral oncology},
  year={2008},
  volume={44 9},
  pages={898-902}
}
The DNA double strand break repair gene XRCC4, an important caretaker of genome stability, is suggested to play a role in the development of human carcinogenesis. However, no evidence has been provided showing that XRCC4 was associated with oral oncology. In this hospital-based case-control study, the association of XRCC4 G-1394T (rs6869366), intron 3 (rs28360071), intron 7 (rs28360317), and intron 7 (rs1805377) polymorphisms with oral cancer risk in a Taiwanese population was first… CONTINUE READING