A novel single-cell DNA fingerprinting method successfully distinguishes sibling human embryos.

@article{Treff2010ANS,
  title={A novel single-cell DNA fingerprinting method successfully distinguishes sibling human embryos.},
  author={Nathan R. Treff and Jing Su and Xin Tao and Kathleen A. Miller and Brynn Levy and Richard T. Scott},
  journal={Fertility and sterility},
  year={2010},
  volume={94 2},
  pages={477-84}
}
OBJECTIVE To validate a novel system for embryonic DNA fingerprinting which can reliably distinguish sibling embryos from each other. DESIGN Prospective, randomized, and blinded study. SETTING Academic center for reproductive medicine. PATIENT(S) Blastomeres were obtained from discarded and transferred embryos from six patients undergoing IVF treatment. INTERVENTION(S) None. MAIN OUTCOME MEASURE(S) Single lymphocytes from sibling cell lines and blastomeres from sibling day 3 human… CONTINUE READING
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