A novel role of hydrogen peroxide in Kaposi sarcoma-associated herpesvirus reactivation.

Abstract

Reactivation of Kaposi sarcoma-associated herpesvirus (KSHV) from latency for lytic replication plays a pivotal role in the development of KS tumors. However, the physiological factors of KSHV reactivation in KS patients remain undefined. Two recent studies independently discovered that the reactive oxygen species (ROS) H(2)O(2) induces KSHV reactivation in… (More)
DOI: 10.4161/cc.10.19.17299

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