A novel role for sox7 in Xenopus early primordial germ cell development: mining the PGC transcriptome.

@article{Butler2018ANR,
  title={A novel role for sox7 in Xenopus early primordial germ cell development: mining the PGC transcriptome.},
  author={Amanda M Butler and Dawn A Owens and Lingyu Wang and Mary Lou King},
  journal={Development},
  year={2018},
  volume={145 1}
}
Xenopus primordial germ cells (PGCs) are determined by the presence of maternally derived germ plasm. Germ plasm components both protect PGCs from somatic differentiation and begin a unique gene expression program. Segregation of the germline from the endodermal lineage occurs during gastrulation, and PGCs subsequently initiate zygotic transcription… CONTINUE READING