A novel purine nucleoside transporter whose expression is up-regulated in the short stumpy form of the Trypanosoma brucei life cycle.

@article{Sanchez2004ANP,
  title={A novel purine nucleoside transporter whose expression is up-regulated in the short stumpy form of the Trypanosoma brucei life cycle.},
  author={Marco Antonio Garc{\'i}a Sanchez and Scott B Drutman and Marleen T J van Ampting and Keith Matthews and Scott M Landfear},
  journal={Molecular and biochemical parasitology},
  year={2004},
  volume={136 2},
  pages={
          265-72
        }
}
Purine nucleoside and nucleobase transporters play a vital role in the metabolism and survival of Trypanosoma brucei because this parasitic protozoan is unable to synthesize purines de novo and thus must acquire preformed purines from its hosts. These parasites express a variety of nucleoside and nucleobase permeases with diverse substrate specificities and distinct patterns of expression during the trypanosome life cycle. We report here that expression of the newly characterized T. brucei… CONTINUE READING

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