A novel purification procedure for recombinant human serum albumin expressed in Pichia pastoris.

Abstract

Plasma-derived human serum albumin (pHSA) has important applications in many clinical indications, including blood loss, serious burn, or hemorrhagic shock. The limited supply and potential infectious pathogen contamination of pHSA have stimulated the development of recombinant human serum albumin (rHSA). However, rHSA often entraps endogenous or exogenous… (More)
DOI: 10.1016/j.pep.2018.04.012

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