A novel protein with a fibrinogen-like domain involved in the innate immune response of Marsupenaeus japonicus.

@article{Chai2012ANP,
  title={A novel protein with a fibrinogen-like domain involved in the innate immune response of Marsupenaeus japonicus.},
  author={Ying-Mei Chai and Qian Zhu and Shanshan Yu and Xiaofan Zhao and Jinxing Wang},
  journal={Fish & shellfish immunology},
  year={2012},
  volume={32 2},
  pages={307-15}
}
Fibrinogen-related proteins play important roles in innate immunity. We isolated a fibrinogen-related protein gene (MjFREP1) in kuruma shrimp Marsupenaeus japonicus. MjFREP1 encoded a protein of 270 amino acids, including a 223 amino acid fibrinogen-like domain. Quantitative real-time polymerase chain reaction analysis shows that MjFREP1 is mainly expressed in the gills and the expression is significantly upregulated by Vibrio anguillarum, Staphylococcus aureus, or white spot syndrome virus… CONTINUE READING

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