A novel protein kinase family in Plasmodium falciparum is differentially transcribed and secreted to various cellular compartments of the host cell.

@article{Nunes2007ANP,
  title={A novel protein kinase family in Plasmodium falciparum is differentially transcribed and secreted to various cellular compartments of the host cell.},
  author={Marta C. Nunes and J P Dean Goldring and Christian D. Doerig and Artur Scherf},
  journal={Molecular microbiology},
  year={2007},
  volume={63 2},
  pages={391-403}
}
Processes at the surface of Plasmodium falciparum-infected erythrocytes such as antigenic variation and cytoadhesion may be modulated by active signalling between host and parasite. Potential candidates for this role include the putative kinases of the FIKK family. The novel Apicomplexa-specific FIKK gene has expanded in P. falciparum to 20 sequence-related members distributed between 11 chromosomes. Specific antibodies raised against different members indicated that most FIKK proteins locate… CONTINUE READING
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