A novel protein distance matrix based on the minimum arc-length between two amino-acid residues on the surface of a globular protein.

We present a novel protein distance matrix based on the minimum line of arc between two points on the surface of a protein. Two methods for calculating this distance matrix are developed and contrasted. The first method, which we have called TOPOL, is an approximate rule based algorithm consisting of successive rounds of vector addition. The second method… CONTINUE READING