A novel protein, Psp1, essential for cell cycle progression of Schizosaccharomyces pombe is phosphorylated by Cdc2-Cdc13 upon entry into G0-like stationary phase of cell growth.

@article{Jang1997ANP,
  title={A novel protein, Psp1, essential for cell cycle progression of Schizosaccharomyces pombe is phosphorylated by Cdc2-Cdc13 upon entry into G0-like stationary phase of cell growth.},
  author={Young-Joo Jang and Mi Sook Won and Kil Saeng Chung and Doory Kim and Kwang Lae Hoe and Chaeho Park and Han Sang Yoo},
  journal={The Journal of biological chemistry},
  year={1997},
  volume={272 32},
  pages={19993-20002}
}
A novel gene, psp1(+), which functionally complements a temperature-sensitive mutant defective in cell cycle progression both in G1/S and G2/M has been isolated from the genomic and cDNA libraries of Schizosaccharomyces pombe. Disruption of this gene is lethal for cell growth at 30 degrees C indicating that it is an essential gene for vegetative cell growth. Western analysis of the protein by polyclonal antibody made from glutathione S-transferase-Psp1 fusion protein indicated that the Psp1… CONTINUE READING