A novel population of T-cell receptor αβ-bearing thymocytes which predominantly expresses a single Vβ gene family

Abstract

Recent studies have demonstrated that CD3 is expressed on a subset of thymocytes with a CD4−CD8− (double negative) phenotype1,2. At least some of these cells bear the CD3-associated γδ T-cell receptor (TCR γδ)3,4. Here we describe a second subset of double negative thymocytes which expresses CD3-associated αβ receptors (TCR αβ). Surprisingly, these cells… (More)
DOI: 10.1038/329251a0

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