A novel polysaccharide from the seeds of Plantago asiatica L. induces dendritic cells maturation through toll-like receptor 4.

@article{Huang2014ANP,
  title={A novel polysaccharide from the seeds of Plantago asiatica L. induces dendritic cells maturation through toll-like receptor 4.},
  author={Danfei Huang and Shao Ping Nie and Leming Jiang and Ming Yong Xie},
  journal={International immunopharmacology},
  year={2014},
  volume={18 2},
  pages={236-43}
}
In this study, we investigated the effect of a polysaccharide purified from the seeds of Plantago asiatica L. (PLP-2) on the phenotypic and functional maturation of murine bone marrow-derived dendritic cells (DCs) and relevant mechanisms. The results showed that PLP-2 increased the expression of maturation markers major histocompatibility complex II, CD86, CD80, and CD40 on DCs. Consistent with the changes in the phenotypic markers, functional assay for DCs maturation showed that PLP-2… CONTINUE READING