A novel phenotypic dissimilarity method for image-based high-throughput screens

Abstract

Discovering functional relationships of genes through cell-based phenotyping has become an important approach in functional genomics. High-throughput imaging offers the ability to quantitatively assess complex phenotypes after perturbation by RNA interference (RNAi). Such image-based high-throughput RNAi screening studies have facilitated the discovery of… (More)
DOI: 10.1186/1471-2105-14-336

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