A novel peptide-based vaccine candidate with protective efficacy against influenza A in a mouse model.

Abstract

Current influenza vaccines mainly induce antibody responses to the variable hemagglutinin proteins of the virus strains included in the vaccine. Instead, a broadly protective influenza vaccine should aim at inducing antibody- and/or cell-mediated immunity against conserved viral proteins. Vacc-FLU is a peptide based vaccine combining conserved B and T cell… (More)
DOI: 10.1016/j.virol.2017.11.018

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