A novel pattern recognition algorithm to classify membrane protein unfolding pathways with high-throughput single-molecule force spectroscopy

Abstract

MOTIVATION Misfolding of membrane proteins plays an important role in many human diseases such as retinitis pigmentosa, hereditary deafness and diabetes insipidus. Little is known about membrane proteins as there are only very few high-resolution structures. Single-molecule force spectroscopy is a novel technique, which measures the force necessary to pull… (More)
DOI: 10.1093/bioinformatics/btl293

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Cite this paper

@article{Marsico2007ANP, title={A novel pattern recognition algorithm to classify membrane protein unfolding pathways with high-throughput single-molecule force spectroscopy}, author={Annalisa Marsico and Dirk Labudde and K. Tanuj Sapra and Daniel J. Muller and Michael Schroeder}, journal={Bioinformatics}, year={2007}, volume={23 2}, pages={e231-6} }