A novel pathogenic role for microvasculature in inflammatory bowel disease.

@article{Danese2006ANP,
  title={A novel pathogenic role for microvasculature in inflammatory bowel disease.},
  author={Silvio Danese and Alfredo Papa and Franco Scaldaferri and Cristina Graziani and Michele Bonizzi and Alessandro Armuzzi and Giuseppe Fedeli and Giovanni Battista Gasbarrini and Antonio Gasbarrini},
  journal={European review for medical and pharmacological sciences},
  year={2006},
  volume={10 1},
  pages={3-5}
}
Crohn's disease (CD) and ulcerative colitis (UC) are the two major forms of inflammatory bowel disease (IBD). Although their etiology is still unknown, the pathogenic mechanisms underlying intestinal inflammation have made impressive progress in our understanding. In particular, the abnormalities underlying IBD pathogenesis are not restricted to those mediated by classical immune cells such as T and B lymphocytes, macrophages and dendritic cells, but also nonimmune cells. Interestingly… CONTINUE READING