A novel panel of cerebrospinal fluid biomarkers for the differential diagnosis of Alzheimer's disease versus normal aging and frontotemporal dementia.

@article{Simonsen2007ANP,
  title={A novel panel of cerebrospinal fluid biomarkers for the differential diagnosis of Alzheimer's disease versus normal aging and frontotemporal dementia.},
  author={Anja Hviid Simonsen and James McGuire and Vladimir N. Podust and N-O Hagnelius and Torbj{\"o}rn K. Nilsson and E Kapaki and Demetris Vassilopoulos and Gunhild Waldemar},
  journal={Dementia and geriatric cognitive disorders},
  year={2007},
  volume={24 6},
  pages={434-40}
}
BACKGROUND An early and accurate diagnosis of Alzheimer's disease (AD) is important in order to initiate symptomatic treatment with currently approved drugs and will be of even greater importance with the advent of disease-modifying compounds. METHODS Protein profiles of human cerebrospinal fluid samples from patients with AD (n = 85), frontotemporal dementia (n = 20), and healthy controls (n = 32) were analyzed by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry… CONTINUE READING

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