A novel nuclear export signal and a REF interaction domain both promote mRNA export by the Epstein-Barr virus EB2 protein.

@article{Hiriart2003ANN,
  title={A novel nuclear export signal and a REF interaction domain both promote mRNA export by the Epstein-Barr virus EB2 protein.},
  author={Edwige Hiriart and G{\'e}raldine Farjot and Henri Gruffat and Minh Vu Chuong Nguyen and Alain Sergeant and Evelyne Manet},
  journal={The Journal of biological chemistry},
  year={2003},
  volume={278 1},
  pages={335-42}
}
A striking characteristic of mRNA export factors is that they shuttle continuously between the cytoplasm and the nucleus. This shuttling is mediated by specific factors interacting with peptide motifs called nuclear export signals (NES) and nuclear localization signals. We have identified a novel CRM-1-independent transferable NES and two nuclear… CONTINUE READING