A novel multiplex-protein array for serum diagnostics of colon cancer: a case–control study

  title={A novel multiplex-protein array for serum diagnostics of colon cancer: a case–control study},
  author={Stefanie B{\"u}nger and Ulrike Haug and Maria Kelly and Nicole Posorski and Katja Klempt-Giessing and Andrew Cartwright and Stephen Peter Fitzgerald and Vicki Toner and Damien McAleer and Timo Gemoll and Tilman Laubert and Juergen Buening and Klaus Fellermann and H. P. Bruch and Uwe Roblick and Hermann Brenner and Ferdinand von Eggeling and Jens K. Habermann},
  booktitle={BMC Cancer},
More than 1.2 million new cases of colorectal cancer are reported each year worldwide. Despite actual screening programs, about 50% of the patients are diagnosed at advanced tumor stages presenting poor prognosis. Innovative screening tools could aid the detection at early stages and allow curative treatment interventions. A nine target multiplex serum protein biochip was generated and evaluated using a training- and validation-set of 317 highly standardized, liquid nitrogen preserved serum… CONTINUE READING
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