A novel mouse beta-defensin, mBD-6, predominantly expressed in skeletal muscle.

@article{Yamaguchi2001ANM,
  title={A novel mouse beta-defensin, mBD-6, predominantly expressed in skeletal muscle.},
  author={Yu Yamaguchi and Shigetomo Fukuhara and Takahiro Nagase and Takeshi Tomita and Syuji Hitomi and Satoshi Kensuke Kimura and Hidetake Kurihara and Yuta Ouchi},
  journal={The Journal of biological chemistry},
  year={2001},
  volume={276 34},
  pages={31510-4}
}
Defensins comprise a family of cationic antimicrobial peptides that is characterized by the conserved 6 cysteine residues. They are expressed in the epithelial cells of various organs and are identified as key elements in the host defense system at the mucosal surface. We isolated a novel mouse beta-defensin gene from the bacterial artificial chromosome DNA containing the mouse beta-defensin-3 gene. The full-length cDNA was cloned from skeletal muscle cDNA and called mouse beta-defensin-6 (mBD… CONTINUE READING
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