A novel molecular assay to discriminate transcriptional effects caused by xenoestrogens

@article{Koohi2007ANM,
  title={A novel molecular assay to discriminate transcriptional effects caused by xenoestrogens},
  author={Mohammad Kazem Koohi and Norbert Walther and Richard Ivell},
  journal={Molecular and Cellular Endocrinology},
  year={2007},
  volume={276},
  pages={45-54}
}
A phenotypic definition of the term estrogen has become increasingly problematic due to the multiple modes of estrogen action which can now be defined by differing nuclear and membrane receptors for the classic ligand, 17beta-estradiol, and by the multiple signalling pathways that are consequently addressed. This has led to the term xenoestrogen being largely determined by whatever assay system is used for its definition. Here we describe a novel and simple matrix for a transfection system… CONTINUE READING

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