A novel modified nucleoside found at the first position of the anticodon of methionine tRNA from bovine liver mitochondria.

@article{Moriya1994ANM,
  title={A novel modified nucleoside found at the first position of the anticodon of methionine tRNA from bovine liver mitochondria.},
  author={Jun Moriya and Takashi Yokogawa and Kyoko Wakita and Tadashi Ueda and Ken Nishikawa and Pamela F. Crain and Takeshi Hashizume and Steven C. Pomerantz and James A. McCloskey and Gohta Kawai},
  journal={Biochemistry},
  year={1994},
  volume={33 8},
  pages={2234-9}
}
Methionine tRNA was purified from bovine liver mitochondria, and its nucleotide sequence was determined. The tRNA possesses only three posttranscriptionally modified nucleosides, two pseudouridines in the anticodon and T stems and a previously unknown nucleoside specified by the gene sequence as cytidine, in the first position of the anticodon. Structure analysis of the anticodon nucleoside by mass spectrometry revealed a molecular mass 28 Da greater than that of cytidine, and unmodified ribose… CONTINUE READING

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