A novel modification of the Thrombelastograph assay, isolating platelet function, correlates with optical platelet aggregation.

@article{Craft2004ANM,
  title={A novel modification of the Thrombelastograph assay, isolating platelet function, correlates with optical platelet aggregation.},
  author={Robert M Craft and J. J. J. Chavez and Stuart J Bresee and Dale C. Wortham and Eli Cohen and Roger C. Carroll},
  journal={The Journal of laboratory and clinical medicine},
  year={2004},
  volume={143 5},
  pages={301-9}
}
Flow cytometry, singlet platelet counting, and optical aggregation have been used to monitor clopidogrel and glycoprotein IIb/IIIa (GPIIb/IIIa) platelet antagonists. Optical aggregation is considered the gold standard, but neither it nor flow cytometry is convenient in larger-scale clinical studies or point-of-care systems. Singlet platelet counting, a point-of-care assay correlated with optical platelet aggregation, only provides a measurement of platelet function at a single point in time… CONTINUE READING
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Effect of clopidogrel on platelet aggregation and plasma concentration of fibrinogen in subjects with cerebral or coronary atherosclerotic disease

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