A novel model of cutaneous candidiasis produced in prednisolone-treated guinea-pigs.

@article{Maebashi1994ANM,
  title={A novel model of cutaneous candidiasis produced in prednisolone-treated guinea-pigs.},
  author={Kazunori Maebashi and Takako Itoyama and Katsuhisa Uchida and Nobuo Suegara and Hideyo Yamaguchi},
  journal={Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology},
  year={1994},
  volume={32 5},
  pages={349-59}
}
In an attempt to develop an animal model of cutaneous candidiasis useful for the pre-clinical evaluation of antifungal drugs, experimental cutaneous Candida albicans infections were produced in mature and immature guinea-pigs treated with prednisolone. The morbidity of this model in terms of the extent and the duration of the superficial infection was compared with that of two other reported models: those produced by alloxan treatment, or the use of occlusive dressings. Infected animals were… CONTINUE READING
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