A novel mitochondrial DNA 8597T>C mutation of Leigh syndrome: report of one case.


Leigh syndrome is an early-onset progressive neurodegenerative disorder with a characteristic neuropathology consisting of focal, bilateral lesions in one or more areas of the central nervous system. The brain images of Leigh syndrome are characterized by markedly symmetrical involvement, most frequently of the putamen. We report a 2-year-old girl with… (More)
DOI: 10.1016/j.pedneo.2011.11.012