A novel method of selective ablation of afferent renal nerves by periaxonal application of capsaicin.

@article{Foss2015ANM,
  title={A novel method of selective ablation of afferent renal nerves by periaxonal application of capsaicin.},
  author={Jason D. Foss and Richard David Wainford and William C. Engeland and Gregory D. Fink and John W. Osborn},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2015},
  volume={308 2},
  pages={R112-22}
}
Renal denervation has been shown to lower arterial pressure in some hypertensive patients, yet it remains unclear whether this is due to ablation of afferent or efferent renal nerves. To investigate the role of afferent renal nerves in arterial pressure regulation, previous studies have used methods that disrupt both renal and nonrenal afferent signaling. The present study was conducted to develop and validate a technique for selective ablation of afferent renal nerves that does not disrupt… CONTINUE READING