A novel method for estimating linkage maps.


The goal of linkage mapping is to find the true order of loci from a chromosome. Since the number of possible orders is large even for a modest number of loci, the problem of finding the optimal solution is known as a NP-hard problem or traveling salesman problem (TSP). Although a number of algorithms are available, many either are low in the accuracy of… (More)


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@article{Tan2006ANM, title={A novel method for estimating linkage maps.}, author={Yuan-De Tan and Yun-Xin Fu}, journal={Genetics}, year={2006}, volume={173 4}, pages={2383-90} }