A novel member of the F-box/WD40 gene family, encoding dactylin, is disrupted in the mouse dactylaplasia mutant

@article{Sidow1999ANM,
  title={A novel member of the F-box/WD40 gene family, encoding dactylin, is disrupted in the mouse dactylaplasia mutant},
  author={A. Sidow and Monique S. Bulotsky and A. Kerrebrock and B. Birren and D. Altshuler and R. Jaenisch and Kenneth R Johnson and E. Lander},
  journal={Nature Genetics},
  year={1999},
  volume={23},
  pages={104-107}
}
Early outgrowth of the vertebrate embryonic limb requires signalling by the apical ectodermal ridge (AER) to the progress zone (PZ), which in response proliferates and lays down the pattern of the presumptive limb in a proximal to distal progression. Signals from the PZ maintain the AER until the anlagen for the distal phalanges have been formed. The semidominant mouse mutant dactylaplasia (Dac) disrupts the maintenance of the AER, leading to truncation of distal structures of the developing… Expand
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References

SHOWING 1-10 OF 32 REFERENCES
Dactylaplasia in mice a two-locus model for development anomalies.
  • C. Chai
  • Biology, Medicine
  • The Journal of heredity
  • 1981
A second autosomal split hand/split foot locus maps to chromosome 10q24-q25.
...
1
2
3
4
...