A novel mass assay to measure phosphatidylinositol-5-phosphate from cells and tissues

@article{Ghosh2019ANM,
  title={A novel mass assay to measure phosphatidylinositol-5-phosphate from cells and tissues},
  author={Avishek Ghosh and Sanjeev Sharma and Dhananjay Shinde and Visvanathan Ramya and P. Raghu},
  journal={bioRxiv},
  year={2019}
}
Phosphatidylinositol-5-phosphate (PI5P) is a low abundance lipid proposed to have functions in cell migration, DNA damage responses, receptor trafficking and insulin signalling in metazoans. However, studies of PI5P function are limited by the lack of scalable techniques to quantify its level from cells and tissues in multicellular organisms. Currently, PI5P measurement requires the use of radionuclide labelling approaches that are not easily applicable in tissues or in vivo samples. In this… Expand
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