A novel long noncoding RNA PILRLS promote proliferation through TCL1A by activing MDM2 in Retroperitoneal liposarcoma

@inproceedings{Shao2017ANL,
  title={A novel long noncoding RNA PILRLS promote proliferation through TCL1A by activing MDM2 in Retroperitoneal liposarcoma},
  author={Yebo Shao and Yong Zhang and Ying-yong Hou and Hanxing Tong and Rongyuan Zhuang and Zhengbiao Ji and Binliang Wang and Yuhong Zhou and Weiqi Lu},
  booktitle={Oncotarget},
  year={2017}
}
It is becoming evident that lncRNAs may be an important class of pervasive genes involved in carcinogenesis and metastasis. However, the biological and molecular mechanisms of lncRNAs in retroperitoneal liposarcoma have never been reported. In our study, we found a novel lncRNA PILRLS (Proliferation Interacting LncRNA in Retroperitoneal Liposarcoma), which as an oncogene significantly overexpressed in retroperitoneal liposarcoma. Functions of PILRLS on tumor progression both in vitro and in… CONTINUE READING