A novel label-free electrochemical aptasensor for thrombin based on the {nano-Au/thionine}n multilayer films as redox probes.

@article{Yuan2010ANL,
  title={A novel label-free electrochemical aptasensor for thrombin based on the \{nano-Au/thionine\}n multilayer films as redox probes.},
  author={Yali Yuan and Ruo Yuan and Y. I. Chai and Ying Zhuo and Zhongyuan Liu and Li Mao and Shu Xia Guan and Xiaoqing Qian},
  journal={Analytica chimica acta},
  year={2010},
  volume={668 2},
  pages={171-6}
}
Herein, a novel label-free electrochemical aptasensor based on direct immobilization of the redox probes on an electrode surface was reported. Gold electrode coated Nafion was firstly modified with redox probe-thionine (Thi) through ion exchange adsorption. Then, with the help of chemisorption and electrostatic adsorption, negatively charged nano-Au and… CONTINUE READING