A novel interaction between Rab7b and actomyosin reveals a dual role in intracellular transport and cell migration.

Abstract

Rab proteins are small GTPases that regulate transport between the different compartments of the endomembrane system in eukaryotic cells. Here, we show that Rab7b, a Rab that controls the transport between late endosomes and the trans Golgi network, interacts directly with myosin II. We illustrate the functional relevance of this interaction, demonstrating… (More)
DOI: 10.1242/jcs.155861

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