A novel injectable formulation of 6-fluoro-l-DOPA imaging agent for diagnosis of neuroendocrine tumors and Parkinson's disease.

Abstract

Two [19F]F-l-DOPA (F-DOPA) new β-cyclodextrin (CD)-based dosage forms (FA and FB, respectively) have been studied and their physico-chemical and pharmacological features determined to overcome the administration site reactions showed by the currently used [18F]F-l-DOPA formulation (IASOdopa®) to perform PET-CT diagnosis in oncology (neuroendocrine tumors… (More)
DOI: 10.1016/j.ijpharm.2017.01.038

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Cite this paper

@article{Trapani2017ANI, title={A novel injectable formulation of 6-fluoro-l-DOPA imaging agent for diagnosis of neuroendocrine tumors and Parkinson's disease.}, author={Adriana Trapani and Domenico Tricarico and Antonietta Mele and Fatima Maqoud and Delia Mandracchia and Paola Vitale and Vito Capriati and Giuseppe Di Trapani and Vincenzo Dimiccoli and Anna Maria Tolomeo and Antonio Scilimati}, journal={International journal of pharmaceutics}, year={2017}, volume={519 1-2}, pages={304-313} }